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Those individuals randomized to lifestyle changesincluding 150 minutes/week of exercise and ??7% weightloss had a 58% reduction in the development of diabe-tes as compared to placebo over a 3-year follow-up (7).Those individuals who received the insulin sensitizermetformin had a 31% reduction in diabetes. One-stage exchange surgery needs a meticulous debridement (as described earlier)with excision of all infected or devascularized scar tissue and necrotic bone as well as allbone cement [61]

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A new era in esophageal diagnostics: the image-based paradigmof high-resolution manometry. Relevance of early seizures for in-hospital mortality in acutecerebrovascular disease.

2002 ; However, no clear data are available in humanMcCurnin et al.

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